Preclinical / Non Clinical
Discover Excellence in the Science of Safety
At Liveon Biolabs, we specialize in toxicology, the science that delves deep into the effects of chemicals on biological systems. Our mission is to empower researchers, scientists, and industries with a comprehensive suite of toxicological studies that evaluate the adverse impacts of chemicals, drugs, and substances on living organisms
- Physical state
- Color
- Odor
- Oxidation/reduction analysis
- Flammability assessments for solids
- Flash point determinations for liquids and storage stability evaluations spanning two years
- Miscibility
- Corrosion characteristics
- PH measurements
- Viscosity analysis and the determination of melting and boiling points
- Density measurements
- Dissociation constant determinations
- Partition coefficient evaluations
- Water solubility assessments
- Vapor pressure analysis
- Handle acidity/alkalinity testing
- Moisture content analysis
- Assessments of dustiness
- Flowability
- Solubility in organic solvents
- Surface tension
- Oxidizing properties for both liquids and solid
- Emulsion stability
- Wettability
- Dispersability
- Pourability
- Suspensibility
- Wet sieve testing.Top of Form
- Acute Toxicity
- Eye Irritation/ Serious Eye Damage (in vivo)
- Guinea Pig Maximization
- Inhalation Toxicity
- Pyrogen Test
- Repeated Dose Toxicity
- Skin Irritation / Corrosion (in vivo)
- Skin Sensitization (in vivo)
- Bacterial Reverse Mutation (AMES) Test
- Chromosomal Aberration Test (in vitro)
- Chromosomal Aberration Test (in vivo)
- Cytotoxicity (in vitro)
- Micronucleus Test (in vitro)
- Micronucleus Test (in vivo)
- Mouse Lymphoma Assay (MLA)
- MTT Assay
Dose formulation analysis, stability and homogeneity analysis
LFT(liver function test)
RFT( Renal function test)
Lipid profile
Electrolytes
Urine analysis
Hematology
Agrochemicals
Liveon Biolabs understands how much agrochemicals manufacturers are concerned about crop protection along with safeguarding the environment.
We provide Toxicology Tests as per requirements of global regulatory :
In vivo Toxicology Studies
- Acute Oral Toxicity
- Acute Dermal Toxicity
- Acute Eye Irritation
- Acute Dermal Irritation
- Skin Sensitization
- Local Lymph Node Assay (LLNA) by BrdU ELISA
- 28,90 and 180 Day Oral or Dermal Toxicity Studies
- Uterotrophic and Hershberger assays for endocrine disruption
Genetic Toxicity Studies
- Bacterial Reverse Mutation Test (Ames test)
- In vitro Mammalian Chromosome Aberration Test
- In vitro Micronucleus Test
- In vivo Mammalian Erythrocyte Micronucleus Test
- In vivo Mammalian Bone Marrow Chromosome Aberration Test
Ecotoxicology Studies
Liveon Biolabs is in the process of establishing ecotoxicology studies. However, Liveon Biolabs is associated with other labs to cater to the needs of clients.
Biocompatibility
Liveon Biolabs has years of experience in conducting Biocompatibility tests and is accredited ISO/IEC 17025: 2005 for testing of medical devices. Our expert scientists carefully evaluate your device for its biological compatibility as per ISO, US FDA guidelines for CE Marking and regulatory approvals.
Biocompatibility Tests at Liveon Biolabs
Test for in vitro Cytotoxicity (ISO 10993-5)
- Agarose Overlay
- MEM Elution
- Direct Contact
- Quantitative Test by MTT Test
Tests for irritation and skin sensitization (ISO 10993-10 and USP)
- Intracutaneous Reactivity
- Mucosal Irritation (vaginal, rectal, oral)
- Ocular Irritation
- Intraocular Irritation
- Closed Patch (Buehler) Dermal Irritation
- Guinea Pig Maximization Test
- Local Lymph Node Assay (LLNA) by BrdU ELISA
Test for Systemic Toxicity (ISO 10993-11)
- Acute Systmeic Toxicity
- Sub-Acute Toxicity
- Sub-chronic Toxicity
- Chronic systemic toxicity
- Reproductive Toxicity
Tests for genotoxicity (ISO 10993-3)
- Bacterial Reverse Mutation Test (Ames test)
- in vitro Mammalian Chromosome Aberration Test
- in vitro Micronucleus Test
- in vivo Mammalian Erythrocyte Micronucleus Test
- in vivo Mammalian Bone Marrow Chromosome Aberration Test
Tests for reproductive toxicity (ISO 10993-3)
- Reproductive and Developmental Toxicology Studies
Tests for carcinogenicity (ISO 10993-3)
- Carcinogenicity Test
Hemocompatibility (ISO 10993-4)
- ASTM Hemolysis
- Prothrombin time (PT)
- Complement assay (C3a and SC5b-9)
- Partial thromboplastin time (PTT)
- Thrombin time (TT)
Tests for local effects after implantation (ISO 10993-6 and USP)
- Intramuscular Implantation
- Subcutaneous Implantation
- Bone Implantation
- Ocular Implantation
Pyrogenicity
- Rabbit Pyrogen Test
- Rabbit Pyrogen – Material Mediated
USP Plastics (USP Class (I-VI))
- USP I-VI
- USP Systemic Injection Test
- USP Intracutaneous Test
- USP Implant Test
- USP Safety Test
Histopathology & Clinical Pathology
Results of Histopathology and Clinical Pathology is key in study interpretations. Careful handling of tissues and biological samples yields promising results. Our experienced team has thorough understanding of Biological samples from animal origin and they handle each sample with care to avoid artefacts.
Our Histopathology & Clinical Pathology Services Include :
- Sample Collection and Preservation
- Sample Processing, Tissue Processing, Embedding, Sectioning, Slide Preparation, Staining and Slide Evaluation
- Biochemistry Analysis
- Haematology Analysis
- Urine Analysis
- Coagulation Analysis
- Bioanalysis
- Bioassay (in vivo)
- Biocompatibility Studies
- Drug Metabolism & Pharmacokinetic (DMPK)
- Hemocompatibility Studies
- Implantation Studies
- Maximum Tolerated Dose (MTD) Studies
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